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Saturday 16th June

Pre-Congress Workshops & C-HPP Meeting

Venue: Faculty of Medicine; University of Santiago de Compostela, all day.

EuPA Educational Program: Cytoscape

EuBIC workshop

c-HPP meeting

C-HPP and EuPA GC dinners

Sunday 17th June

9:00-13:00
C-HPP meeting (Venue: Faculty of Medicine)
EuPA GC meeting (Venue: Hotel Monumento San Francisco – Sala Columnas)

13:00-17:30
YPIC session (Hotel Monumento San Francisco - Sala Cimabue)

Preliminary program

Plenary Session I: Opening Session & SEProt Honorary Member designation

Chairs: Deborah Penque, Ángel García.

18:30-19:30
The Proteotype: Integrator of Bological Information and Determinator of Phenotypes
Prof. Dr. Ruedi Aebersold. ETH Zurich. Inst. f. Molekulare Systembiologie. Switzerland

Welcome Reception

19:30
Hotel Monumento San Francisco

Monday 18th June

Meet the expert session

7:30-8:15 EUPA YPIC Meet the expert session

Plenary Session II: Proteomics in Cell Biology

Chairs: Montserrat Carrascal, Mercedes Pardo

8:30-9:15
Proteomics and data integration for unraveling the mysteries of spermatogenesis.
Charles Pineau. Protim (Proteomics Core Facility Biogenouest). Irset – Inserm U1085, Rennes, France

9:15-10:00
OMICS tools to characterize platelet function.
Albert Sickmann. Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund, Germany

10:00-11:00
Coffee Break & Posters

Topic Session I: Cellular Proteomics

Chairs: Charles Pineau, Mercedes Pardo

11:00-11:20
Searching for Ghost Proteins Interactome.
Cardon Tristan. PRISM, France.

11:20-11:40
Dissecting the Molecular Portrait of Ground State Pluripotency with Quantitative Proteomics
Javier Muñoz. CNIO, Spain.

11:40-11:55
The histone code studied by bottum-up label-free Mass Spectrometry: how comprehensive is the current picture?
Maarten Dhaenens. Ghent University, Belgium.

11:55-12:10
Quantitative proteomics and whole transcriptomics sequencing of Progeria-derived cells point to a key role of nucleotide metabolism in premature aging
María del Carmen Arufe. UDC, Spain.

12:10-12-25
Macrophages reactivation inside glioma microenvironments through PC1/3 inhibition associated with TLR3 activation
Melanie Rose. PRISM, France.

12:25-12:40
Role of exosomal Cx43 in melanoma progression
Adrián Varela. INIBIC, Spain.

12:40-12:55
Mechanisms of IL-33 activation through proteolytic maturation by environmental allergens analyzed by mass spectrometry
Anne Gonzalez de Peredo. CRNS, France.

Topic Session II: PTMs.

Chairs: Albert Sickmann, Montserrat Carrascal

11:00–11:20
A missing value-compatible algorithm to calculate absolute phosphorylation stoichiometry from LFQ-DIA, SILAC and TMT-based data.
Alexander Hogrebe. NNF Center for Protein Research, Denmark.

11:20-11:40
Histidine phosphorylation as another dimension of the phosphoproteome.
Clement Potel. Utrecht University, The Netherlands.

11:40–12:00
Comprehensive quantification of the modified proteome reveals oxidative heart damage in mitochondrial heteroplasmy.
Jesús Vázquez. CNIC, Spain.

12:00–12:20
Quantitative phosphoproteomics reveals novel phosphosites downstream Kappa-opioid receptor in human spermatozoa.
Itziar Urizar-Arenaza. University of the Basque Country, Spain.

12:20–12:40
Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome.
Ugo Mayor. University of the Basque Country, Spain.

12:40–13:00
Application of thiol redox proteomics to clinical samples – valve heart disease and ischemic stroke.
Antonio Martínez-Ruiz. IIS-IP, Spain.

13:00-15:00
thermo fisher

Thermofisher Lunch Seminar
Expanding the Biomolecular Structural Analysis Capabilities using Orbitrap Technology.
Sega Ndiaye, Thermo Fisher Scientific
Fast, Sensitive and Quantitative Phosphoproteomics for Large-scale Cell Perturbation Analysis.
Jesper Olsen, Novo Nordisk Foundation Center for Protein Research, Denmark

Lunch & Posters

Plenary Session III: Systems biology and quantitative proteomics thermo fisher

Chairs: Juan Antonio Vizcaíno, Cristina Ruiz-Romero

15:00-15:45
Dissecting EGF receptor signaling in-vivo by Quantitative Interaction Proteomics and Phosphoproteomics.
Jesper Olsen. Novo Nordisk Foundation Center for Protein Research. University of Copenhagen. Denmark

15:45-16:30
Using a mass spectrometer as a microscope: a physical map of a human cell.
Anne-Claude Gingras. The Lunenfeld-Tanenbaum Research Institute. Toronto. Canada.

16:30-16:45
Break & Posters

Topic Session III: From Proteomics to integrated omics: data management and interpretation.

Chairs: Juan Antonio Vizcaíno and Cristina Ruiz-Romero

16:45-17:05
Creating a comprehensive functional map of the human phospho-proteome.
JA Vizcaíno. EMBL-EBI, UK.

17:05-17:25
Proteogenomics of adenosine-to-inosine RNA editing in model organisms.
Sergei Moshkovskii. Institute of Biomedical Chemistry Moscow, Russia.

17:25-17:45
Systems proteomics of gene expression.
Georg Kustatscher. Wellcome trust Edinburgh, UK.

17:45-18:00
ProteoRE, a Galaxy-based infrastructure for annotating and interpreting proteomics data.
Yves Vandenbrouck. CEA, INSERM, France.

18:00-18:15
VSClust: Feature-based variance-sensitive clustering of proteomics data.
Veit Schwämmle. University of South Denmark, Denmark.

18:15-18:30
Scop3P: the bridge between human phosphosites, protein structure and PRIDE data.
Pathmanaban Ramasamy. VIB-UGent, Belgium.

18:30-18:45
Benefits of rapid profile of modifications with SpecOMS
Dominique Tessier. INRA, France.

Topic Session IV: Microorganisms and microbiota

Chairs: Concha Gil, Ana Varela-Coelho

16:45-17:00
Rapid determination of host-pathogen quaternary protein structures in complex biological samples
Johan Malmström. Lund University, Sweden.

17:00-17:15
Absolute Quantification of Pseudomonas aeruginosa TonB-dependent Transporters Using PRM and SWATH-MS.
Sandra Söderholm. University of Basel, Switzerland.

17:15-17:30
Signatures of commensal and pathogenic Staphylococcus epidermidis: a genomic and proteomic approach
Ana Varela-Coelho. ITQB NOVA, Portugal.

17:30-17:45
Data-independent acquisition: hight-throughput proteomic tool to monitor the response of Candida albicans to human macrophages.
Ahinara Amador. UCM, Spain.

17:45-18:00
Listeria monocytogenes planktonic and sessile cells adaptation to different temperatures seen through shotgun proteomics
Tiago Santos. INRA, France.

18:00-18:15
Candida albicans induces changes in human macrophage proteins involved in RNA-splicing, protein synthesis and apoptosis.
Catarina Oliveira Vaz. UCM, Spain.

18:15-18:30
An unbiased metaproteomic approach to describe the mucosal microbiome of HIV-exposed african infant cohort
Suereta Fortuin. University of Cape Town, South Africa.

18:30-18:45
Quantitative proteomics to study N and C metabolisms in the marine Cyanobacterium prochlorococcus
Guadalupe Gómez Baena. University of Córdoba, Spain.

18:45-19:30
SEProt GC Meeting

Tuesday 19th

Meet the expert session

7:30-8:15 EUPA YPIC Meet the expert session

Plenary Session IV: Clinical Proteomics  SCIEX LOGO RGB

Chairs: Ignacio Casal, Francisco Amado

8:30-9:15
MALT1 paracaspase activity and scaffolding regulation of linear ubiquitination, NFkB and therapeutic rescue.
Chris Overall. University of British Columbia. Vancouver. Canada

9:15-10:00
(Phospho)Proteomics for marker and target discovery in cancer
Prof. Dr. Connie R. Jimenez. VU University Medical Center. Amsterdam. The Netherlands

10:00-11:00
Coffee Break & Posters

Topic Session V: Disease Proteomics I

Chairs: Ignacio Casal and Francisco Amado.

11:00-11:15
Cancer Moonshot Center Lund, Sweden
György Marko-Varga. Lund University, Sweden.

11:15-11:30
HMGB1 interactome analysis in epithelial cancer cells.
Aida Inés Barreiro-Alonso. UDC, Spain.

11:30-11:45
Parallel reaction monitoring-based strategy to validate colorectal cancer biomarkers in serum/plasma.
Consuelo Marín-Vicente. CIB-CSIC, Spain.

11:45-12:00
Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma
Félix Elortza. CIC BioGUNE, Spain.

12:00-12:15
Early proteome dynamics of glioblastoma cells during the oncolytic adenovirus DNX-2401 infection
Andrea Gonzalez Morales. Navarrabiomed, Spain.

12:15-12:30
Investigating protein interactions of the long non-coding RNA MALAT-1 in brain tumors
Maike Langini. MPL – BMFZ, Düsseldorf, Germany

12:30-12:45
High-resolution quantitative proteomics applied to the discovery of biomarkers of innate immune response in tuberculosis.
Jesús Mateos. CSIC, Spain.

12:45-13:00
A MALDI-TOF MS Comparative Approach for Disclosing a Novel Peptide Biomarker Signature of Gingivitis
Chiara Villella. University “Magna Graecia”, Italy.

Topic Session VI: Proteomics in Agriculture Biotechnology and Animal Proteomics

Chair: Jesús Jorrín

11:00-11:20
Natural variation and pan-omics approach drived discovery of novel wood quality biomarkers in Pinus pinaster Aiton
Luis Valledor. University of Oviedo, Spain.

11:20-11:40
ChloroKB: a web-application for the integration of knowledge related to chloroplast metabolic network
Myriam Ferro. CEA, France.

11:40-12:00
Differentiation of the geographycal origil of tiger nut (Cyperus esculentus) through a proteomic approach
Lorea Rivera Beldarrain. University of the Basque Country, Spain.

12:00-12:15
Immunoproteomic approaches to solve the proteomic profile of olive pollen and its complex allergogram
Pablo San Segundo Acosta. UCM, Spain.

12:15-12:30
The alliance of proteogenomics & multiplexed targeted ecotoxico-proteomics for environmental monitoring of river water quality
Duarte Gouveia. CEA Marcoule, France.

12:30-12:45
Study of myofibrillar proteome from pre-slaughter stressed animals using liquid isoelectric focusing and mass spectrometry.
Claudia Fuente García. IATA, Spain.

12:45-13:00
Cultivation type makes a difference: the proteome of monolayers and spheroids of canine osteosarcoma cells.
Ingrid Miller. University of Veterinary Medicine, Austria.

13:00-15:00
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Bruker Daltonics Lunch Seminar
Towards deeper, faster and more sensitive proteomics

Lunch & Posters

Plenary Session V: Technology & Methodology Advances in Proteomics

Chairs: Félix Elortza, Jose Luis Capelo

15:00-15:45
The RNA binding proteome in time and space.
Kathryn Lilley. Cambridge Centre for Proteomics. University of Cambridge. UK

15:45-16:30
Making use and sense of more data in mass spectrometry imaging
Benjamin Balluff. Maastrich University, Netherlands

16:30-16:45
Break & Posters

Topic Session VII: Standardization & Technological Innovation

Chairs: Félix Elortza, José Luis Capelo

16:45-17:00
Determination of site specific phosphorylation ratios in proteins with targeted mass spectrometry
Lennard Dekker. Erasmus MC, The Netherlands.

17:00-17:15
Trapped ion mobility spectrometry with parallel accumulation – serial fragmentation (TIMS-PASEF): pushing the limits of shotgun proteomics analysis
Pierre-Olivier Schmit. Bruker SAS, France.

17:15-17:30
Targeted proteomics method comparison: SRM, PRM and SWATH-MS to quantify proteins in bovine muscle tissues
Joanna Bons. IPHC, France.

17:30-17:45
Towards absolute and generic top-down quantitative proteomics through combination of elemental and molecular mass spectrometry
Francisco Calderon. University of Oviedo, Spain.

17:45-18:00
Protein interaction screen on peptide matrices (PRISMA) dissect motif specific binding partners
Daniel Perez Hernandez. Max Delbruck Center, Berlin, Germany

18:00-18:15
The combination of protein, peptide and lipid MALDI-IMS analysis allows a deeper insight in Molecular Histology
Ibon Iloro. CIC BioGUNE, Spain.

18:15-18:30
Development of a novel LC concept for clinical proteomics
Alexandre Podtelejnikov. EVOSEP, Odense, Denmark

18:30-18:45
Suitability comparison of EDTA-plasma, heparin-plasma and serum for shotgun proteomics
Antonio Núñez Galindo. Nestle Institute of Health Sciences, Lausanne, Switzerland

Topic Session VIII: Disease Proteomics II

Chairs: Ángel García, Jesús Vázquez

16:45-17:10
An update on the Human Plasma Proteome
Jochen Schwenk. SciLifeLab (KTH), Sweden.

17:10-17:30
Protein aggregates enriched from blood as new and promising subproteome for biomarkers discovery in neurodegeneration
Rocco Adiutori. Queen Mary University of London, UK.

17:30-17:50
Deep-Dive in the Proteome of Human Cerebrospinal Fluid: A Comprehensive Database and Resource for the Discovery of Biomarkers and Missing Proteins
Charlotte Macron. Nestlé Institute of Health Sciences, Lausanne, Switzerland

17:50-18:05
Olfactory Proteomic Survey unveils a Stage-dependent Proteostasis Imbalance in Parkinson´s disease
Mercedes Lachén. Navarrabiomed, Spain.

18:05-18:20
A two-step PRM strategy identifies a new biomarker signature in cerebrospinal fluid for multiple sclerosis prognosis
Marin Philippe. University of Montpellier, CNRS INSERM, France.

18:20-18:35
Cardiovascular risk stratification in young population: application of thiol redox proteomics
Nerea Corbacho Alonso. HNP, Spain.

Presentation of the EU-FT-ICR-MS Project

18:35-18:50
Presentation of the EU-FT-ICR-MS Project

YPIC challenge award

19:00-20:00
YPIC challenge award

21:00
Gala Dinner at Hostal dos Reis Católicos 

Wednesday 20th

Plenary Session VI: Top-down proteomics

Chair: Juan J Calvete

8:45-9:30
The Increasingly Important Role of Top-Down Proteomics and the Proteoform in Human Health and Disease
Neil Kelleher. Northwestern University, Evanston, USA

Topic Session IX: Top-down and Chemical Proteomics

Chairs: Juan J Calvete, Carlos Cordeiro

9:30-9:45
A systematic map of protein-metabolite interactions reveals principles of chemical communication
Ilaria Piazza. ETH Zurich, Switzerland.

9:45-10:00
Structural elucidation of proteoforms from Actinobacteria by Top-down MS
Julien Parra. CNRS IPBS, France.

10:00-10:15
An integrated workflow for cross-linking/mass spectrometry
Marta Mendes. Technische Universität Berlin, Germany.

Topic Session X: Food & Nutrition Proteomics

Chairs: Paola Roncada, Miguel Ángel Sentandreu

10:15-10:30
Optimisation of protein extraction for in-depth profiling of the cereal grain proteome
Utpal Bose. C CSIRO, Queensland, Australia

10:30-10:45
Characterization of short digestion-resistant peptides of cow’s milk allergens by digestomics approach
Tanja Cirkovic Velickovic. Ghent University Global Campus, South Korea

10:45-11:00
Differentiation between fresh and frozen–thawed curled octopus using two-dimensional gel and shotgun proteomics
Maria Mazza. Istituto Zooprofilattico Sperimentale del Piemonte, Italy.

11:00-11:30
Coffee Break & Posters

Topic Session XI: Disease Proteomics III

Chairs: Fernando Corrales, Bruno Manadas

11:30-11:45
Multi-omics and functional investigations in hepatic and skeletal muscle mitochondria of pre-diabetic mice
Lisa Kappler. University Hospital of Tübingen, Germany.

11:45-12:00
Exosomes as new players in dedifferentiation and cartilage remodelling in osteoarthritis
Marta Varela Eirín. INIBIC, Spain.

12:00-12:15
An optimized protocol for the analysis of laser microdissected muscle tissue samples for mass spectrometry
Britta Eggers. Ruhr-University Bochum, Germany.

12:15-12:30
Verification of rheumatoid arthritis activity biomarkers by targeted proteomics.
Lucía González Rodríguez. INIBIC, Spain.

12:30-12:45
Integrating Serum Proteomics, Metabolomics and Lipidomics to Study the Effect of Sport Activity
Marcello Manfredi. University of Piemonte Orientale, Italy.

12:45-13:00
Unravelling a knee Osteoarthritis-associated Autoantibody profile for early diagnosis: Data from the Osteoarthritis Initiative
Maria Camacho Encina. INIBIC, Spain.

13:00-15:00

Biognosys Logo Color

Biognosys Lunch Seminar

Longitudinal Plasma Profiling with Stable Isotope Standards and Data- Independent Acquisition Analysis
Sebastian Müller, Biognosys

Lunch & Posters

Plenary Session VII: Closing Session

Chairs: Deborah Penque, Ángel García

15:00-16:00
A proteomic map of the target landscape of clinical kinase inhibitors.
Bernhard Küster. Technische Universität München, Germany

16:00-16:45
Juan Pablo Albar EuPA and SEProt Awards ceremony.

16:45-17:15
Young Investigator Prize, Industry Award, and poster prizes.

17:15-17:30
Closing remarks

Educational program co-organized by EuPA, SEProt and Proteored/isciii.

iscii proteored FEDER ISCIII MINECO 2017