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Saturday 16th June

Pre-Congress Workshops & C-HPP Meeting

Venue: Faculty of Medicine; University of Santiago de Compostela, all day.

EuPA Educational Program: Cytoscape

EuBIC workshop

c-HPP meeting

C-HPP and EuPA GC dinners

Sunday 17th June

C-HPP meeting (Venue: Faculty of Medicine)
EuPA GC meeting (Venue: Hotel Monumento San Francisco – Sala Columnas)

YPIC session (Hotel Monumento San Francisco - Sala Cimabue)

Preliminary program

Registration Opening
Hotel Monumento San Francisco

Plenary Session I: Opening Session & SEProt Honorary Member designation

Chairs: Deborah Penque, Ángel García.

The Proteotype: Integrator of Bological Information and Determinator of Phenotypes
Prof. Dr. Ruedi Aebersold. ETH Zurich. Inst. f. Molekulare Systembiologie. Switzerland

Welcome Reception

Hotel Monumento San Francisco

Monday 18th June

Meet the expert session

7:30-8:15 EUPA YPIC Meet the expert session

Plenary Session II: Proteomics in Cell Biology

Chairs: Montserrat Carrascal, Mercedes Pardo

Proteomics and data integration for unraveling the mysteries of spermatogenesis.
Charles Pineau. Protim (Proteomics Core Facility Biogenouest). Irset – Inserm U1085, Rennes, France

OMICS tools to characterize platelet function.
Albert Sickmann. Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund, Germany

Coffee Break & Posters

Topic Session I: Cellular Proteomics

Chairs: Charles Pineau, Mercedes Pardo

Searching for Ghost Proteins Interactome.
Cardon Tristan. PRISM, France.

Dissecting the Molecular Portrait of Ground State Pluripotency with Quantitative Proteomics
Javier Muñoz. CNIO, Spain.

The histone code studied by bottum-up label-free Mass Spectrometry: how comprehensive is the current picture?
Maarten Dhaenens. Ghent University, Belgium.

Quantitative proteomics and whole transcriptomics sequencing of Progeria-derived cells point to a key role of nucleotide metabolism in premature aging
María del Carmen Arufe. UDC, Spain.

Macrophages reactivation inside glioma microenvironments through PC1/3 inhibition associated with TLR3 activation
Melanie Rose. PRISM, France.

Role of exosomal Cx43 in melanoma progression
Adrián Varela. INIBIC, Spain.

Mechanisms of IL-33 activation through proteolytic maturation by environmental allergens analyzed by mass spectrometry
Anne Gonzalez de Peredo. CRNS, France.

Topic Session II: PTMs.

Chairs: Albert Sickmann, Montserrat Carrascal

A missing value-compatible algorithm to calculate absolute phosphorylation stoichiometry from LFQ-DIA, SILAC and TMT-based data.
Alexander Hogrebe. NNF Center for Protein Research, Denmark.

Histidine phosphorylation as another dimension of the phosphoproteome.
Clement Potel. Utrecht University, The Netherlands.

Comprehensive quantification of the modified proteome reveals oxidative heart damage in mitochondrial heteroplasmy.
Jesús Vázquez. CNIC, Spain.

Quantitative phosphoproteomics reveals novel phosphosites downstream Kappa-opioid receptor in human spermatozoa.
Itziar Urizar-Arenaza. University of the Basque Country, Spain.

Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome.
Ugo Mayor. University of the Basque Country, Spain.

Application of thiol redox proteomics to clinical samples – valve heart disease and ischemic stroke.
Antonio Martínez-Ruiz. IIS-IP, Spain.

thermo fisher

Thermofisher Lunch Seminar
Expanding the Biomolecular Structural Analysis Capabilities using Orbitrap Technology.
Sega Ndiaye, Thermo Fisher Scientific
Fast, Sensitive and Quantitative Phosphoproteomics for Large-scale Cell Perturbation Analysis.
Jesper Olsen, Novo Nordisk Foundation Center for Protein Research, Denmark

Lunch & Posters

Plenary Session III: Systems biology and quantitative proteomics thermo fisher

Chairs: Juan Antonio Vizcaíno, Cristina Ruiz-Romero

Dissecting EGF receptor signaling in-vivo by Quantitative Interaction Proteomics and Phosphoproteomics.
Jesper Olsen. Novo Nordisk Foundation Center for Protein Research. University of Copenhagen. Denmark

Using a mass spectrometer as a microscope: a physical map of a human cell.
Anne-Claude Gingras. The Lunenfeld-Tanenbaum Research Institute. Toronto. Canada.

Break & Posters

Topic Session III: From Proteomics to integrated omics: data management and interpretation.

Chairs: Juan Antonio Vizcaíno and Cristina Ruiz-Romero

Creating a comprehensive functional map of the human phospho-proteome.
JA Vizcaíno. EMBL-EBI, UK.

Proteogenomics of adenosine-to-inosine RNA editing in model organisms.
Sergei Moshkovskii. Institute of Biomedical Chemistry Moscow, Russia.

Systems proteomics of gene expression.
Georg Kustatscher. Wellcome trust Edinburgh, UK.

ProteoRE, a Galaxy-based infrastructure for annotating and interpreting proteomics data.
Yves Vandenbrouck. CEA, INSERM, France.

VSClust: Feature-based variance-sensitive clustering of proteomics data.
Veit Schwämmle. University of South Denmark, Denmark.

Scop3P: the bridge between human phosphosites, protein structure and PRIDE data.
Pathmanaban Ramasamy. VIB-UGent, Belgium.

Benefits of rapid profile of modifications with SpecOMS
Dominique Tessier. INRA, France.

Topic Session IV: Microorganisms and microbiota

Chairs: Concha Gil, Ana Varela-Coelho

Rapid determination of host-pathogen quaternary protein structures in complex biological samples
Johan Malmström. Lund University, Sweden.

Absolute Quantification of Pseudomonas aeruginosa TonB-dependent Transporters Using PRM and SWATH-MS.
Sandra Söderholm. University of Basel, Switzerland.

Signatures of commensal and pathogenic Staphylococcus epidermidis: a genomic and proteomic approach
Ana Varela-Coelho. ITQB NOVA, Portugal.

Data-independent acquisition: hight-throughput proteomic tool to monitor the response of Candida albicans to human macrophages.
Ahinara Amador. UCM, Spain.

Listeria monocytogenes planktonic and sessile cells adaptation to different temperatures seen through shotgun proteomics
Tiago Santos. INRA, France.

Candida albicans induces changes in human macrophage proteins involved in RNA-splicing, protein synthesis and apoptosis.
Catarina Oliveira Vaz. UCM, Spain.

An unbiased metaproteomic approach to describe the mucosal microbiome of HIV-exposed african infant cohort
Suereta Fortuin. University of Cape Town, South Africa.

Quantitative proteomics to study N and C metabolisms in the marine Cyanobacterium prochlorococcus
Guadalupe Gómez Baena. University of Córdoba, Spain.

SEProt GC Meeting

Guided Tour: The four squares of Santiago Cathedral. Meeting point: in front of San Francisco Hotel Monumento Main Entrance

Tuesday 19th

Meet the expert session

7:30-8:15 EUPA YPIC Meet the expert session

Plenary Session IV: Clinical Proteomics  SCIEX LOGO RGB

Chairs: Ignacio Casal, Francisco Amado

MALT1 paracaspase activity and scaffolding regulation of linear ubiquitination, NFkB and therapeutic rescue.
Chris Overall. University of British Columbia. Vancouver. Canada

(Phospho)Proteomics for marker and target discovery in cancer
Prof. Dr. Connie R. Jimenez. VU University Medical Center. Amsterdam. The Netherlands

Coffee Break & Posters

Topic Session V: Disease Proteomics I

Chairs: Ignacio Casal and Francisco Amado.

Cancer Moonshot Center Lund, Sweden
György Marko-Varga. Lund University, Sweden.

HMGB1 interactome analysis in epithelial cancer cells.
Aida Inés Barreiro-Alonso. UDC, Spain.

Parallel reaction monitoring-based strategy to validate colorectal cancer biomarkers in serum/plasma.
Consuelo Marín-Vicente. CIB-CSIC, Spain.

Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma
Félix Elortza. CIC BioGUNE, Spain.

Early proteome dynamics of glioblastoma cells during the oncolytic adenovirus DNX-2401 infection
Andrea Gonzalez Morales. Navarrabiomed, Spain.

Investigating protein interactions of the long non-coding RNA MALAT-1 in brain tumors
Maike Langini. MPL – BMFZ, Düsseldorf, Germany

High-resolution quantitative proteomics applied to the discovery of biomarkers of innate immune response in tuberculosis.
Jesús Mateos. CSIC, Spain.

A MALDI-TOF MS Comparative Approach for Disclosing a Novel Peptide Biomarker Signature of Gingivitis
Chiara Villella. University “Magna Graecia”, Italy.

Topic Session VI: Proteomics in Agriculture Biotechnology and Animal Proteomics

Chair: Luis Valledor

Natural variation and pan-omics approach drived discovery of novel wood quality biomarkers in Pinus pinaster Aiton
Luis Valledor. University of Oviedo, Spain.

ChloroKB: a web-application for the integration of knowledge related to chloroplast metabolic network
Myriam Ferro. CEA, France.

Differentiation of the geographycal origil of tiger nut (Cyperus esculentus) through a proteomic approach
Lorea Rivera Beldarrain. University of the Basque Country, Spain.

Immunoproteomic approaches to solve the proteomic profile of olive pollen and its complex allergogram
Pablo San Segundo Acosta. UCM, Spain.

The alliance of proteogenomics & multiplexed targeted ecotoxico-proteomics for environmental monitoring of river water quality
Duarte Gouveia. CEA Marcoule, France.

Study of myofibrillar proteome from pre-slaughter stressed animals using liquid isoelectric focusing and mass spectrometry.
Claudia Fuente García. IATA, Spain.

Cultivation type makes a difference: the proteome of monolayers and spheroids of canine osteosarcoma cells.
Ingrid Miller. University of Veterinary Medicine, Austria.

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Bruker Lunch Seminar

Towards deeper, faster and more sensitive proteomics.

Unleashing the power of QTOF technology for proteomics with TIMS and PASEF
Pierre-Olivier Schmit, Bruker Daltonique, France

The Stable Isotope Labeling Kinetics (SILK) road: turnover, synthesis and breakdown of proteins in vivo
Jérôme Vialarêt, University of Montpellier, LBPC- IRMB, CHU Montpellier, Montpellier, France

Lunch & Posters

Plenary Session V: Technology & Methodology Advances in Proteomics

Chairs: Félix Elortza, Jose Luis Capelo

The RNA binding proteome in time and space.
Kathryn Lilley. Cambridge Centre for Proteomics. University of Cambridge. UK

Making use and sense of more data in mass spectrometry imaging
Benjamin Balluff. Maastrich University, Netherlands

Break & Posters

Topic Session VII: Standardization & Technological Innovation

Chairs: Félix Elortza, José Luis Capelo

Determination of site specific phosphorylation ratios in proteins with targeted mass spectrometry
Lennard Dekker. Erasmus MC, The Netherlands.

Trapped ion mobility spectrometry with parallel accumulation – serial fragmentation (TIMS-PASEF): pushing the limits of shotgun proteomics analysis
Pierre-Olivier Schmit. Bruker SAS, France.

Targeted proteomics method comparison: SRM, PRM and SWATH-MS to quantify proteins in bovine muscle tissues
Joanna Bons. IPHC, France.

Towards absolute and generic top-down quantitative proteomics through combination of elemental and molecular mass spectrometry
Francisco Calderon. University of Oviedo, Spain.

Protein interaction screen on peptide matrices (PRISMA) dissect motif specific binding partners
Daniel Perez Hernandez. Max Delbruck Center, Berlin, Germany

The combination of protein, peptide and lipid MALDI-IMS analysis allows a deeper insight in Molecular Histology
Ibon Iloro. CIC BioGUNE, Spain.

Development of a novel LC concept for clinical proteomics
Alexandre Podtelejnikov. EVOSEP, Odense, Denmark

Suitability comparison of EDTA-plasma, heparin-plasma and serum for shotgun proteomics
Antonio Núñez Galindo. Nestle Institute of Health Sciences, Lausanne, Switzerland

Topic Session VIII: Disease Proteomics II

Chairs: Ángel García, Jesús Vázquez

An update on the Human Plasma Proteome
Jochen Schwenk. SciLifeLab (KTH), Sweden.

Protein aggregates enriched from blood as new and promising subproteome for biomarkers discovery in neurodegeneration
Rocco Adiutori. Queen Mary University of London, UK.

Deep-Dive in the Proteome of Human Cerebrospinal Fluid: A Comprehensive Database and Resource for the Discovery of Biomarkers and Missing Proteins
Charlotte Macron. Nestlé Institute of Health Sciences, Lausanne, Switzerland

Olfactory Proteomic Survey unveils a Stage-dependent Proteostasis Imbalance in Parkinson´s disease
Mercedes Lachén. Navarrabiomed, Spain.

A two-step PRM strategy identifies a new biomarker signature in cerebrospinal fluid for multiple sclerosis prognosis
Marin Philippe. University of Montpellier, CNRS INSERM, France.

Cardiovascular risk stratification in young population: application of thiol redox proteomics
Nerea Corbacho Alonso. HNP, Spain.

Presentation of the EU-FT-ICR-MS Project

Presentation of the EU-FT-ICR-MS Project

YPIC challenge award

YPIC challenge award

Gala Dinner at Hostal dos Reis Católicos 

Wednesday 20th

Plenary Session VI: Top-down proteomics

Chair: Juan J Calvete

The Increasingly Important Role of Top-Down Proteomics and the Proteoform in Human Health and Disease
Neil Kelleher. Northwestern University, Evanston, USA

Topic Session IX: Top-down and Chemical Proteomics

Chairs: Juan J Calvete, Carlos Cordeiro

A systematic map of protein-metabolite interactions reveals principles of chemical communication
Ilaria Piazza. ETH Zurich, Switzerland.

Structural elucidation of proteoforms from Actinobacteria by Top-down MS
Julien Parra. CNRS IPBS, France.

An integrated workflow for cross-linking/mass spectrometry
Marta Mendes. Technische Universität Berlin, Germany.

Topic Session X: Food & Nutrition Proteomics

Chairs: Paola Roncada, Miguel Ángel Sentandreu

Optimisation of protein extraction for in-depth profiling of the cereal grain proteome
Utpal Bose. C CSIRO, Queensland, Australia

Characterization of short digestion-resistant peptides of cow’s milk allergens by digestomics approach
Tanja Cirkovic Velickovic. Ghent University Global Campus, South Korea

Differentiation between fresh and frozen–thawed curled octopus using two-dimensional gel and shotgun proteomics
Maria Mazza. Istituto Zooprofilattico Sperimentale del Piemonte, Italy.

Coffee Break & Posters

Topic Session XI: Disease Proteomics III

Chairs: Fernando Corrales, Bruno Manadas

Multi-omics and functional investigations in hepatic and skeletal muscle mitochondria of pre-diabetic mice
Lisa Kappler. University Hospital of Tübingen, Germany.

Exosomes as new players in dedifferentiation and cartilage remodelling in osteoarthritis
Marta Varela Eirín. INIBIC, Spain.

An optimized protocol for the analysis of laser microdissected muscle tissue samples for mass spectrometry
Britta Eggers. Ruhr-University Bochum, Germany.

Verification of rheumatoid arthritis activity biomarkers by targeted proteomics.
Lucía González Rodríguez. INIBIC, Spain.

Integrating Serum Proteomics, Metabolomics and Lipidomics to Study the Effect of Sport Activity
Marcello Manfredi. University of Piemonte Orientale, Italy.

Unravelling a knee Osteoarthritis-associated Autoantibody profile for early diagnosis: Data from the Osteoarthritis Initiative
Maria Camacho Encina. INIBIC, Spain.


Biognosys Logo Color

Biognosys Lunch Seminar

Longitudinal Plasma Profiling with Stable Isotope Standards and Data- Independent Acquisition Analysis
Sebastian Müller, Biognosys

Use of a novel DIA acquisition for enhanced throughput analysis with an exploratory targeted reagent strategy in Clinical Proteomics Research David Heywood, Waters Corporation.

Lunch & Posters

Plenary Session VII: Closing Session

Chairs: Deborah Penque, Ángel García

A proteomic map of the target landscape of clinical kinase inhibitors.
Bernhard Küster. Technische Universität München, Germany

Juan Pablo Albar EuPA and SEProt Awards ceremony.

Young Investigator Prize, Industry Award, and poster prizes.

Closing remarks

Educational program co-organized by EuPA, SEProt and Proteored/isciii.

iscii proteored FEDER ISCIII MINECO 2017